Fragmento

A 48-year-old man was admitted to hospital following four days of having suffered diarrhea and a febrile episode on the same day as he consulted. The diarrhea had increased to 6 episodes during the 12 hours before admission, regardless of the administration of loperamide or low doses of dexamethasone. He referred to no other symptoms upon admission. The patient had a background of having had malignant melanoma stage IV due to the presence of cerebral, hepatic and peritoneal metastases. Such diagnosis was made at 43 years of age due to the presence of a malar lesion. A cerebral metastases appeared on the right frontal lobe four years after diagnosis (aged 47) which required surgical excision followed by stereotactic radiosurgery in the residual cavity. Local-regional recurrence led to it being managed with surgical excision plus brachytherapy. The appearance of a metastatic lesion required pulmonary wedge resection during the same year. He underwent an intestinal resection for the management of some other metastatic lesions five months prior to admission. Positron-emission tomography (PET/CT) developed one month before admission revealed the presence of 3 hepatic lesions, a right temporal one and visceral metastases due to the presence of various infracentimetric peritoneal nodules and a proximal small bowel lesion (around 3 cm diameter). The patient started treatment with ipilimumab after these findings, receiving the second dose 11 days before being admitted to hospital.

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2012-07-11   |   1,061 visitas   |   1 valoraciones

Vol. 1 Núm.1. Abril 2012 Pags. 67-69 Rev Colomb Hematol Oncolo 2012; 1(1)